Thorne Vitamin B12

Vitamin B12 is the one essential nutrient with almost no reliable plant source at all, which puts vegan and vegetarian athletes in a fundamentally different risk category than they'd be for nearly any other vitamin. Standard B12 supplements often use cyanocobalamin, a form your liver has to process and convert before your body can actually use it.

Thorne's Vitamin B12 is an active form of vitamin B12 that supports heart and nerve health, normal circadian rhythms, and healthy methylation

Nothing to convert – Methylcobalamin is the biologically active, tissue-ready form of B12, unlike cyanocobalamin, which requires your liver to process out a cyanide molecule before it becomes useful.

Supports red blood cell formation – B12 plays a direct role in producing the red blood cells that carry oxygen through your bloodstream during training.

Supports nerve signaling and communication – B12 contributes to maintaining the myelin sheath, the insulation around nerve cells that keeps signal transmission fast and clean.

Methylcobalamin works as a cofactor for methionine synthase, an enzyme involved in recycling homocysteine and supporting the body's broader methylation processes, the same chemical reactions tied to energy production, mood regulation, and DNA repair. Because it's already in its active form, your body doesn't need to strip a cyanide group and attach a methyl group the way it does with cyanocobalamin, the more common and less expensive form found in many standard supplements.

How to Use Thorne Vitamin B12

Dose: Take one capsule one to three times daily, with or without food, or as recommended by your health-care practitioner. If you notice a stimulating effect from B vitamins, take it earlier in the day.

Vegan or vegetarian: This is one of the few nutrients where supplementation matters more than dietary tweaks, since animal products are essentially the only reliable natural source.

Individuals with Leber's disease, a rare inherited eye condition, should avoid high doses of vitamin B12. Consult your healthcare practitioner before use if pregnant.